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- _2 value "Although direct pharmacological inhibition of PDE2 activity with erythro-9-(2-hydroxyl-3-nonyl)adenine increases L-type Ca2+ currents in cardiomyocytes, and contracts these cells, the overall magnitude of this effect is species-specific and probably influenced by several factors, including basal levels of adenylyl and guanylyl cyclases as well as the level of PDE3 activity in these cells (Vandecasteele et al., 2001)." provenance.
- _2 wasQuotedFrom 12920188 provenance.