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- _4 value "and has now been found to be secreted from adipocytes (Boucher et al. 2005). It is synthesized as a 77 amino acid preproprotein, which is cleaved to a 55 amino acid product and then to further products, the biologically active form apparently being apelin-36 (Tatemoto et al. 1998). Apelin expression and circulating levels are increased in hyperinsulinaemia-associated obesities, including in humans, and in cell culture its expression rises after adipocyte differentiation." provenance.
- _4 wasQuotedFrom 16026420 provenance.