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- _4 value "In addition to cyt-c, mitochondria also release several other proteins, including endonuclease G, AIF (a deathmodulating flavoprotein), and IAP antagonists SMAC (DIABLO) and OMI (HtrA2) (see below), some of which may promote caspase- independent (nonapoptotic) cell death (Kroemer and Reed, 2000). IAP-antagonists, SMAC (Diablo) and HtrA2 (Omi), are sequestered inside mitochondria, becoming released into the cytosol during apoptosis (Reed, 2002)." provenance.
- _4 wasQuotedFrom 12559172 provenance.