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- _4 value "Shox2 controls the expression of Ihh, Runx2 and Runx3 in the stylopodial. In the Shox2-/- limbs, at E11.5 Ihh was expressed in a wild-type pattern in all skeletal condensations including the presumptive stylopodial element (Fig. 4B). However, by E12.5 Ihh expression was almost completely lost in the Shox2-/- stylopod (Fig. 4). Interestingly, Ihh expression in the mutant zeugopod remained normal, suggesting a specific role of Shox2 in maintaining Ihh expression in the stylopod. " provenance.
- _4 wasQuotedFrom 17481601 provenance.