Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAyPkVDK8UFG10TTkYQ4Z0zKU_oe0bshdXOmei52DURIc#_6> ?p ?o ?g. }
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- _6 value "LDL, in pathophysiological concentrations, affect the IGF-I signaling pathway at multiple levels: 1) they induce phosphorylation of IGF-I receptor beta and IRS-1 in a time- and dose-dependent manner; 2) they up-regulate IRS-1-associated PI3 kinase/Akt activation in response to IGF-I at early times; and 3) they show additive effects with IGF-I on extracellular signal-regulated MAPK 1/2 phosphorylation." provenance.
- _6 wasQuotedFrom 11606453 provenance.