Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAya_dphVLN25HS4moOYIgT2vewnqLfKcOoW092rSapDQ#_4> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _4 value "Pentraxin 3 (PTX3) is the first long pentraxin identified. Long pentraxins consist of a C-terminal pentraxin domain, which has sequence similarity to C-reactive protein (CRP) and serum amyloid P (SAP) component (the classic short pentraxins), and of an unrelated N-terminal portion. PTX3 is made by diverse cell types, most prominently endothelial cells, macrophages and dendritic cells, in response to primary inflammatory signals (e.g. interleukin-1 (IL-1), tumour necrosis factor (TNF), lipopolysaccharide (LPS)). It binds diverse ligands, including microbial moieties, C1q and apoptotic cells. Evidence suggests that PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility." provenance.
- _4 wasQuotedFrom 12763682 provenance.