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- _4 value "ANG II-mediated MAPK activation is followed by an increase in c-fos (activated by ERK) and c-jun (activated by JNK) gene expression, as well as increased AP-1 activity. AP-1 is a transcription factor complex (formed from dimerization of c-Jun and c-Fos) and ultimately influences cell differentiation, migration, and adhesion by binding to gene promoter sequences (191). " provenance.
- _4 wasQuotedFrom 16870827 provenance.