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- _3 value "Western blots showed that SMCs did not express DAP kinase protein when cultured in the absence of agLDL. In contrast, strong upregulation of DAP kinase protein could be detected after 2 days of agLDL treatment (Figure 3A). DAP kinase expression was associated with enhanced levels of the tumor suppressor protein p53. We also observed a progressive increase in Bax and TNF receptor 2 expression during foam cell formation. Furthermore, it was demonstrated that agLDL could significantly induce (3-fold) both DAP kinase and Bax gene transcription (Figure 3B)." provenance.
- _3 wasQuotedFrom 12482829 provenance.