Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAzOaP13eRyCMUPCYnP_x9M2oBsj1RaaDp8694dSy764w#_4> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _4 value "Hypoxia-induced mitogenic factor (HIMF) HIMF = Retnla ... We showed that HIMF induced phosphorylation of the IkappaB kinase signalsome and, subsequently, IkappaBalpha, leading to activation of NF-kappaB. Meanwhile, VCAM-1 production was correspondingly upregulated. Blocking NF-kappaB signaling pathway by expression of dominant-negative mutants of IkappaB kinase and IkappaBalpha suppressed HIMF-induced VCAM-1 upregulation. HIMF also strongly induced phosphorylation of Akt" provenance.
- _4 wasQuotedFrom 16709959 provenance.