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- _4 value "CSE (1, 2.5, and 5%) dose dependently and significantly decreased SIRT1 activity after 4 and 24 h (P 0.001). Sirtuin inhibitors suramin and nicotinamide abolished sirtuin activity, whereas resveratrol, a SIRT1 activator, significantly increased sirtuin activity (P 0.001) (Fig. 1)." provenance.
- _4 wasQuotedFrom 17041012 provenance.