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- _6 value "The plasmin-plasminogen activator system and matrix metalloproteinases (MMPs) cooperate in this degradation [20]. uPA converts plasminogen into plasmin, a serine protease that degrades fibrin and other matrix proteins, and activate several MMPs, including stromelysin- 1 (MMP-3), collagenase-1 (MMP-1), type IV collagenases (MMP-2 and MMP-9) [21]. FGF1, FGF2, and FGF4 upregulate uPA and MMPs production in endothelial cells." provenance.
- _6 wasQuotedFrom 15863032 provenance.