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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "At early developmental stages,SGK is first expressed in the decidua and yolk sac and is highly expressed in heart tissue, blood vessels and lung buds, suggesting a potential role for this protein kinase in heart development and or blood vessel formation [53]. As reviewed elsewhere [61-63], the phosphoinositide dependent protein kinase-1 (PDK1) is activated directly down-stream of PI 3-kinase [22, 28]. Full stimulation of SGK enzymatic activity requires the PDK-1 dependent phosphorylation at amino acid residue threonine 256 within the activation loop of SGK, and phosphorylation at serine 422 in the carboxyterminal domain, presumably by a PDK-1-like enzyme [22, 28]." provenance.
- _5 wasQuotedFrom 12649597 provenance.
- assertion hadPrimarySource 12649597 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "1.4" provenance.