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- _3 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _2 value " In the presence of CPT, topo I forms a covalent intermediate with the 3'-phosphate end of the broken DNA strand (5) . This single-strand nick lesion is believed to convert into an irreversible double-strand break after it encounters the replication fork machinery in S phase. This unusual form of DNA damage induces a signaling cascade that is propagated by ATM-family kinases in human cells (6) , which phosphorylate numerous targets involved in transcription, DNA repair, cell cycle arrest, and apoptosis." provenance.
- _2 wasQuotedFrom 15026349 provenance.
- assertion hadPrimarySource 15026349 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom _2 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- large_corpus.bel authoredBy _3 provenance.
- large_corpus.bel version "20131211" provenance.